What Makes CMV Inconspicuous?
If our immune system becomes deficient, which can happen for different reasons and under different circumstances, then the virus can become active and dominant. People that undergo surgery for like an organ transplant or bone marrow transplant, or even people in intense wards because of acute sepsis, for example, are vulnerable to the reactivation of the virus.
Once the virus reactivates, it can cause disease that can lead to death. CMV is the most common infectious cause of birth defects. It is a virus that is not controlled through vaccination, and it can shut it off at a critical moment. Thus it is difficult to develop a vaccine against this virus.
It is a unique virus because it contains the largest genome of any virus known in human medicine and it can induce the most potent immune response that has been described ever in human medicine. While CMV is a very common virus, it would also seem that nobody has ever heard of it before, until it’s too late.
How CMV is Transmitted
CMV is spread through bodily secretion such as saliva, urine, and sexual contact. But once infected, people don’t even know that they have it. Many will experience light symptoms or no symptoms at all.
However, if you’re pregnant, and catch Cytomegalovirus or CMV, and you transmit it to your unborn baby, it becomes one of the major causes of birth defects. It causes disabilities more than down syndrome and other diseases.